Study 5
Name of Study: Oedema Inhibiting Effect Of Procyanidin
Conducted by: G. Blazso and M. Gabor
Published in: Act Physiologica Academiae Hungaricae, Tomus 56 (2) pp. 235-240
Publication date: February 1, 1980 Where study conducted: Institute of Pharmacodynamics, University Medical School, Szoged, Hungary
Material used for study: Masquelier's OPC extract from Vitis Vinifera (grape seeds)
In-vivo study: Yes
Category of animal subjects: male Sprague-Dawley CPY rats
Dosages used: 10, 20 or 40mg/kg 1.P.
Summary/Abstract: We have demonstrated that Leucocyanidol, the extract from peanut pellicles or pine tree bark, has antagonistic qualities vis-a-vis the hyaluronidase and from this viewpoint, appears to be one of the most active vitamin P substances. This observation not only explains the effects of Leucocyanidol on vascular resistance but also its anti-anaphylactic qualities.